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Future models of care will increasingly integrate: biomarkers, functional and body composition assessment behavioural science to address patient priotities digital monitoring and longitudinal data more personalised and adaptive nutrition support Importantly, their value will depend on how effectively they are integrated into scalable, clinically meaningful models of care - not deployed in isolation

doi:10.1016/j.jhep.2017.07.005

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202,203 Essentially, the imported disulphide-containing proteins undergo cathepsin-catalysed degradation in the lysosome, leading to the formation of cystine, which is then effluxed by the cystinosin transporter into the cytosol, where it is reduced to cysteine in a process that requires NADPH, leading to the formation of oxidised glutathione